Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413331 | 0.76 | — | — | |
| SCHEMBL16389544 | 0.76 | — | — | |
| SCHEMBL27734839 | 0.75 | MAPK1 (0.35) | MAPK1ALDH1A1TDP1RAB9ATSHR | |
| SCHEMBL28102868 | 0.75 | ALDH1A1 (0.35) | MAPK1ALDH1A1TDP1SMN1; SMN2RAB9A | |
| SCHEMBL31281659 | 0.74 | — | — | |
| SCHEMBL3057644 | 0.74 | — | — | |
| SCHEMBL28286119 | 0.70 | TUBB8B (0.38) | MAPK1MAPT | |
| SCHEMBL2418235 | 0.69 | HSD17B10 (0.43) | MAPK1ALDH1A1SMN1; SMN2RAB9AMAPT | |
| Formic Acid SCHEMBL27770735 | 0.67 | CHRNB2 (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6260229 | 0.66 | TSHR (0.53) | MAPK1ALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245685-B | The production method of (acetylene-1,2-diyl) double (isobenzofuran-1,3-diketone) | 聂克斯姆化学有限公司 | 2016-09-07 | — | — | CN | disclosed |