Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14119948 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ALOX15TSHRRECQL | |
| SCHEMBL19109 | 0.84 | HSD17B10 (0.52) | ALDH1A1HSD17B10ALOX15TSHRRECQL | |
| SCHEMBL1028272 | 0.79 | THRB (0.43) | ALDH1A1HSD17B10TSHRRECQLCYP3A4 | |
| SCHEMBL11566429 | 0.78 | ESR1 (0.52) | ALDH1A1HSD17B10ALOX15TSHRRECQL | |
| SCHEMBL2812358 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HSD17B10ALOX15TSHRRECQL | |
| SCHEMBL31287202 | 0.78 | HSD17B10 (0.46) | ALDH1A1HSD17B10ALOX15TSHRRECQL | |
| SCHEMBL2812889 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HSD17B10ALOX15TSHRRECQL | |
| SCHEMBL297381 | 0.78 | HSD17B10 (0.46) | ALDH1A1HSD17B10ALOX15TSHRRECQL | |
| SCHEMBL13038931 | 0.77 | HSD17B10 (0.45) | ALDH1A1HSD17B10ALOX15TSHRRECQL | |
| SCHEMBL296892 | 0.75 | CA2 (0.46) | ALDH1A1HSD17B10ALOX15TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | ALDH1A1 401/4885HSD17B10 534/4885ALOX15 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.