Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27725450 | 0.89 | HDAC1 (0.64) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20597404 | 0.86 | HDAC2 (0.73) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9180061 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1569112 | 0.81 | POLB (0.62) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9178786 | 0.80 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14041747 | 0.80 | HDAC2 (0.54) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7450980 | 0.79 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11281109 | 0.79 | NPC1 (0.52) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3512351 | 0.79 | HDAC2 (0.63) | ALDH1A1SMN1; SMN2HDAC2HDAC8HDAC6 | |
| SCHEMBL5430589 | 0.79 | HDAC2 (0.63) | ALDH1A1SMN1; SMN2HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451678-A | Inhibition of histone deacetylase 6 (HDAC 6) | 艾科尼佐治疗股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119212707-A | Oxadiazole HDAC6 inhibitors and uses thereof | 艾科尼佐治疗股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-111936136-B | Novel imidazopyrimidine compounds and uses thereof | 儿童医学中心公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118055926-A | ROCK2 inhibitors and uses thereof | 哈佛大学的校长及成员们 | 2024-05-17 | — | — | CN | disclosed |
| CN-118043459-A | Chemically modified oligonucleotides | 菲奥医药公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117794560-A | Stapled peptides and methods thereof | 弗格制药有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117136182-A | Cationic lipids based on \"God\" buffers | 翻译生物公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-116710116-A | Beta-sheet femoral bridge peptide | Ｘｅｎｏ－Ｉｎｔｅｒｆａｃｅ株式会社 | 2023-09-05 | — | — | CN | disclosed |
| CN-116546989-A | N-acetylgalactosamine (GalNAc) derived compounds and oligonucleotides | 阿达尔克斯制药有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116323638-A | Stapled peptides and methods thereof | 弗格制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115135765-A | Chemically modified oligonucleotides targeting bromodomain-containing protein 4(BRD4) for immunotherapy | 菲奥医药公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-109563509-B | Reduced size self-delivering nucleic acid compounds targeting long non-coding RNAs | 菲奥医药公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-113226377-A | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-105682666-B | Activation of human iNKT cells using glycolipids | 中央研究院 | 2021-06-01 | — | — | CN | disclosed |
| CN-108135923-B | Nucleic acid molecules targeting superoxide dismutase 1(SOD1) | 菲奥医药公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-112384517-A | Heteroaryl compounds and uses thereof | 新旭生技股份有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-111936136-A | Novel imidazopyrimidine compounds and uses thereof | 儿童医学中心公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-111201024-A | Chemically modified oligonucleotides | 菲奥医药公司 | 2020-05-26 | — | — | CN | disclosed |
| CN-105960265-A | Method for treating wound healing using chemically modified oligonucleotides | 阿克赛医药公司 | 2016-09-21 | — | — | CN | disclosed |