Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9180061 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL28103443 | 0.80 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL20597404 | 0.72 | HDAC2 (0.73) | ALDH1A1SMN1; SMN2CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL27725450 | 0.71 | HDAC1 (0.64) | ALDH1A1SMN1; SMN2CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL11739652 | 0.71 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4EMAPTCYP3A4 | |
| SCHEMBL2407962 | 0.70 | HDAC1 (0.57) | ALDH1A1SMN1; SMN2KDM4EMAPTLMNA | |
| SCHEMBL7450980 | 0.69 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL9184984 | 0.69 | TSHR (0.50) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7478303 | 0.68 | HDAC2 (0.53) | ALDH1A1SMN1; SMN2KDM4EMAPTRAB9A | |
| SCHEMBL3786487 | 0.68 | HDAC2 (0.53) | ALDH1A1SMN1; SMN2CYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | claimed |