Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292693 | 0.85 | ATR (0.43) | ATRABL1MT-CO2PDK2TUBB4A | |
| SCHEMBL5782935 | 0.84 | ATR (0.42) | ATRABL1MT-CO2PDK2TUBB4A | |
| SCHEMBL27707339 | 0.76 | ABL1 (0.44) | ABL1PDK2TUBB4ATUBBTUBA3C | |
| SCHEMBL1110874 | 0.74 | NQO2 (0.52) | ABL1PDK2TUBB4ATUBBTUBA3C | |
| SCHEMBL18147226 | 0.74 | ALDH1A1 (0.43) | ATRMT-CO2TUBB4ATUBBTUBA3C | |
| SCHEMBL30485169 | 0.74 | ALDH1A1 (0.43) | ATRMT-CO2TUBB4ATUBBTUBA3C | |
| SCHEMBL5781341 | 0.74 | KDM4E (0.49) | ATRABL1PDK2CA12CA1 | |
| SCHEMBL27688093 | 0.73 | TUBB4A (0.41) | ABL1PDK2TUBB4ATUBBTUBA3C | |
| SCHEMBL27413839 | 0.72 | TUBB4A (0.40) | ABL1PDK2TUBB4ATUBBTUBA3C | |
| SCHEMBL1017951 | 0.71 | PDK1 (0.49) | ATRPDK2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103547567-B | There is the Hedgelog protein antagonist of zinc bound fraction | 柯瑞斯公司 | 2016-09-14 | — | — | CN | disclosed |