Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212845 | 0.79 | CYP19A1 (0.81) | CYP19A1SMN1; SMN2CYP3A4LMNATSHR | |
| SCHEMBL9466346 | 0.76 | HSPB1 (0.61) | TSHRMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL9808021 | 0.76 | CYP19A1 (0.54) | CYP19A1SMN1; SMN2CYP3A4LMNATSHR | |
| SCHEMBL309863 | 0.76 | LMNA (0.61) | CYP19A1SMN1; SMN2LMNATSHRALOX5 | |
| SCHEMBL9789477 | 0.76 | CYP19A1 (0.77) | CYP19A1SMN1; SMN2CYP3A4LMNATSHR | |
| SCHEMBL16541066 | 0.76 | CYP19A1 (0.77) | CYP19A1SMN1; SMN2CYP3A4LMNATSHR | |
| SCHEMBL9789472 | 0.76 | CYP19A1 (0.77) | CYP19A1SMN1; SMN2CYP3A4LMNATSHR | |
| SCHEMBL29395454 | 0.76 | CYP19A1 (0.77) | CYP19A1SMN1; SMN2CYP3A4LMNATSHR | |
| SCHEMBL13158993 | 0.76 | CYP19A1 (0.48) | CYP19A1SMN1; SMN2CYP3A4LMNATSHR | |
| SCHEMBL462857 | 0.74 | ALOX5 (0.49) | CYP19A1SMN1; SMN2CYP3A4LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146283-A | A kind of industrialized process for preparing of 1,4,5,8 naphthalenetetracarbacidic acidics | 朱婧瑶 | 2016-11-23 | — | — | CN | claimed |