Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAT1 | O14929 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 10/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.32 |
| ▸ | MYLK4 | Q86YV6 | 4/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797499 | 0.76 | HCAR2 (0.35) | — | |
| SCHEMBL32681721 | 0.75 | CTSS (0.43) | — | |
| SCHEMBL27809896 | 0.73 | MME (0.32) | HAT1EP300MME | |
| SCHEMBL28160803 | 0.73 | CA1 (0.50) | — | |
| SCHEMBL28807145 | 0.71 | MAPT (0.41) | — | |
| SCHEMBL31527715 | 0.71 | MAPT (0.41) | — | |
| SCHEMBL10344624 | 0.70 | FOLH1 (0.50) | — | |
| SCHEMBL28875042 | 0.70 | NAPRT (0.40) | HAT1EP300 | |
| SCHEMBL31527760 | 0.69 | KEAP1 (0.39) | — | |
| SCHEMBL28223454 | 0.69 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083814-A | A kind of substituted pyridine connection pyrazoles acetamides and its preparation method and application | 浙江工业大学 | 2016-11-09 | — | — | CN | disclosed |