Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110457 | 0.85 | PIK3CA (0.50) | ACHECCNT1CCNA2CDK2CDK9 | |
| SCHEMBL30600608 | 0.82 | SUV39H2 (0.38) | ACHESUV39H2ADRB1 | |
| SCHEMBL26684341 | 0.81 | ACHE (0.55) | ACHESUV39H2 | |
| SCHEMBL7904079 | 0.76 | SORD (0.55) | ACHEGBA1 | |
| SCHEMBL18228454 | 0.76 | SORD (0.55) | ACHEGBA1 | |
| SCHEMBL12597157 | 0.74 | KDM4E (0.55) | ACHE | |
| SCHEMBL8549105 | 0.73 | GBA1 (0.56) | ACHEDYRK1ACCNT1CCNA2CDK2 | |
| SCHEMBL18228033 | 0.73 | ACHE (0.47) | ACHEDYRK1ACCNT1CCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL10504874 | 0.73 | KDM4E (0.53) | ACHE | |
| SCHEMBL13806030 | 0.72 | SORD (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470924-B | Imidazopyrazines derivant as TNF active regulator | UCB生物制药私人有限公司 | 2016-11-09 | — | — | CN | disclosed |