Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.54 |
| ▸ | GRN | P28799 | 2/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | CTSA | P10619 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586183 | 0.97 | LMNA (0.60) | LMNAALDH1A1GAAMAPTRAB9A | |
| SCHEMBL6339006 | 0.87 | OPRM1 (0.57) | LMNAMAPTRAB9AOPRM1OPRD1 | |
| SCHEMBL21656526 | 0.87 | LMNA (0.63) | LMNAALDH1A1GAARAB9AMAPK1 | |
| SCHEMBL12157057 | 0.85 | LMNA (0.65) | LMNAALDH1A1MAPK1KDM4EL3MBTL1 | |
| SCHEMBL15684885 | 0.85 | LMNA (0.61) | LMNAALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL619879 | 0.85 | LMNA (0.61) | LMNAALDH1A1MAPTRAB9AOPRM1 | |
| SCHEMBL21656974 | 0.84 | LMNA (0.60) | LMNAMAPTRAB9AOPRM1OPRD1 | |
| SCHEMBL31646829 | 0.83 | L3MBTL1 (0.54) | LMNAALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL21656686 | 0.83 | LMNA (0.59) | LMNAALDH1A1OPRM1OPRD1MAPK1 | |
| SCHEMBL29596790 | 0.83 | RXFP1 (0.56) | ALDH1A1GAAMAPTRAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105939998-A | Heteroaryl compounds as btk inhibitors and uses thereof | 默克专利有限公司 | 2016-09-14 | — | — | CN | disclosed |