Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENO1 | P06733 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27744868 | 0.98 | ALDH1A1 (0.39) | ENO1PRKCAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL12015477 | 0.84 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2GAANPSR1POLB | |
| SCHEMBL8440453 | 0.84 | ALDH1A1 (0.41) | ENO1PRKCAALDH1A1GAANPSR1 | |
| SCHEMBL12015478 | 0.82 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2GAANPSR1POLB | |
| SCHEMBL12422447 | 0.82 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2NPSR1POLBMAPT | |
| SCHEMBL9906132 | 0.82 | PRKCA (0.33) | ENO1PRKCAGAANPSR1POLB | |
| SCHEMBL12989425 | 0.82 | SIGMAR1 (0.42) | ENO1PRKCAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9625099 | 0.80 | NPSR1 (0.47) | ALDH1A1GAANPSR1POLBCHRM2 | |
| SCHEMBL15248890 | 0.79 | KMT2A (0.47) | ALDH1A1GAANPSR1POLBMAPT | |
| SCHEMBL19432673 | 0.79 | KMT2A (0.47) | ALDH1A1GAANPSR1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661398-A | Spiral shell-lactams and two-spiral shells-lactams nmda receptor regulator and application thereof | 阿普廷伊克斯股份有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-106103445-A | Pyrazolo [1,5 A] pyrimidine 5,7 diamine compound and their therapeutic use as CDK inhibitor | 癌症研究技术有限公司 | 2016-11-09 | — | — | CN | disclosed |