Propene

Propene

SCHEMBL28106961

C=CC.CCO[Si](C)(COC(=O)C(C)(C)C)OCC

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.31
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28860692 0.91 PRKCA (0.35) PRKCACYP4F2CYP4A11ALDH1A1CYP3A4
SCHEMBL18014646 0.77 CYP4F2 (0.36) CYP4F2CYP4A11
SCHEMBL27991163 0.77 PRKCA (0.35) PRKCACYP4F2CYP4A11ALDH1A1CYP3A4
SCHEMBL28168410 0.77 PRKCA (0.31) PRKCACYP4F2CYP4A11
SCHEMBL105934 0.75 TSHR (0.46) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL28071214 0.74 PRKCA (0.36) PRKCACYP4F2CYP4A11ALDH1A1CYP3A4
SCHEMBL28244999 0.74 PRKCA (0.33) PRKCA
SCHEMBL28137287 0.72 PRKCA (0.37) PRKCA
SCHEMBL3959259 0.71 HCAR2 (0.47) ALDH1A1
SCHEMBL1468131 0.70 HCAR2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106029342-B Self-sealing article 3M创新有限公司 2019-06-28 CN disclosed
CN-106029342-A Self-sealing article 3M创新有限公司 2016-10-12 CN disclosed