Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | IAPP | P10997 | 3/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | RPA1 | P27694 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22046175 | 0.87 | PIK3CA (0.48) | PIK3CADAOPYGLRPA1HDAC1 | |
| SCHEMBL5200292 | 0.87 | FFAR1 (0.51) | PIK3CARPA1 | |
| SCHEMBL15517814 | 0.86 | PIK3CA (0.47) | PIK3CADAOPYGLRPA1HDAC1 | |
| SCHEMBL27753241 | 0.85 | IAPP (0.45) | IAPPPYGLMAPTPNMTTAAR1 | |
| SCHEMBL7330823 | 0.82 | PYGL (0.60) | PIK3CAIAPPPYGLALDH1A1MAPT | |
| SCHEMBL3578367 | 0.82 | IAPP (0.49) | DAOIAPPHDAC1HDAC6ALDH1A1 | |
| SCHEMBL28566998 | 0.81 | CYP1A2 (0.53) | PIK3CARPA1HDAC1HDAC3HDAC2 | |
| SCHEMBL901787 | 0.79 | CYP4F2 (0.56) | PIK3CAALDH1A1MAPTALOX15TSHR | |
| SCHEMBL4847962 | 0.79 | PNMT (0.43) | PIK3CADAOMAPTPNMTTAAR1 | |
| SCHEMBL3264645 | 0.79 | MAPT (0.47) | PIK3CADAORPA1HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103936819-B | Hepatitis c virus inhibitors | 百时美施贵宝公司 | 2016-11-16 | — | — | CN | disclosed |