Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 1/20 | 0.57 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | TDO2 | P48775 | 2/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.47 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957979 | 0.75 | CCNT1 (0.57) | CCNT1CDK9HASPINTDO2QPCT | |
| SCHEMBL22482294 | 0.74 | CCNT1 (0.62) | CCNT1CDK9HASPINIMPDH2IMPDH1 | |
| SCHEMBL3319584 | 0.72 | CYP11B2 (0.56) | CYP11B2CYP17A1CYP11B1FASN | |
| SCHEMBL6773157 | 0.72 | CYP11B2 (0.56) | CYP11B2CYP17A1CYP11B1 | |
| SCHEMBL6439562 | 0.72 | CYP11B2 (0.56) | CYP11B2CYP17A1CYP11B1 | |
| SCHEMBL19128281 | 0.72 | CYP11B2 (0.70) | CYP11B2CYP17A1CYP11B1 | |
| SCHEMBL10707057 | 0.71 | PIK3CD (0.68) | CYP11B2CYP17A1CYP11B1FASN | |
| SCHEMBL31663544 | 0.71 | XDH (0.55) | CYP11B2CYP17A1CYP11B1 | |
| SCHEMBL15667411 | 0.71 | CCNT1 (0.62) | CCNT1CDK9HASPINIMPDH2IMPDH1 | |
| SCHEMBL11653917 | 0.70 | NR4A2 (0.58) | HASPINTDO2QPCTQPCTLNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193725-B | Organic compound | 诺华股份有限公司 | 2016-11-16 | — | — | CN | disclosed |