Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830565 | 0.83 | MEN1 (0.42) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL5358083 | 0.81 | MEN1 (0.55) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL29878480 | 0.81 | MEN1 (0.55) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL28150854 | 0.79 | MEN1 (0.46) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL28107582 | 0.78 | ALDH1A1 (0.37) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL782649 | 0.78 | MEN1 (0.46) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL19869567 | 0.76 | MEN1 (0.44) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL30817486 | 0.76 | MEN1 (0.44) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL19061360 | 0.76 | MEN1 (0.42) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL2046823 | 0.75 | SMN1; SMN2 (0.68) | MEN1KMT2ALMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117117-B | A kind of preparation method of the fluorenyl benzindole derivative containing halogen | 中节能万润股份有限公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-106117117-A | A kind of preparation method of the fluorenyl benzindole derivant containing halogen | 中节能万润股份有限公司 | 2016-11-16 | — | — | CN | disclosed |