SCHEMBL30817486

SCHEMBL30817486

Brc1ccccc1-c1cccc2c1C(c1ccccc1)(c1ccccc1)c1ccccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
OPRK1 P41145 1/20 0.44
MAPK1 P28482 2/20 0.42
ALDH1A1 P00352 1/20 0.42
PDK2 Q15119 3/20 0.37
POLB P06746 1/20 0.35
HSP90AA1 P07900 1/20 0.35
CFTR P13569 1/20 0.34
GOPC Q9HD26 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP19A1 P11511 2/20 0.33
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19869567 1.00 MEN1 (0.44) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL782649 0.91 MEN1 (0.46) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL26808385 0.88 ALDH1A1 (0.43) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL30805720 0.84 LMNA (0.47) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL30726518 0.82 MEN1 (0.48) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL19293857 0.82 MEN1 (0.48) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL29922848 0.82 MEN1 (0.48) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL6830565 0.82 MEN1 (0.42) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL19759990 0.82 LMNA (0.42) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL29490147 0.82 LMNA (0.42) MEN1KMT2ALMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119012888-A Organic electroluminescent device and display device comprising same 烟台显华科技集团股份有限公司 2024-11-22 CN disclosed
CN-117326955-A Novel compound and organic light-emitting element comprising same 东进世美肯株式会社 2024-01-02 CN disclosed