Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846604 | 0.89 | KDM4E (0.38) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL29573891 | 0.89 | KDM4E (0.38) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL19164650 | 0.87 | S100A4 (0.37) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL782649 | 0.84 | MEN1 (0.46) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL28107264 | 0.83 | MEN1 (0.47) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL30817486 | 0.82 | MEN1 (0.44) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL19869567 | 0.82 | MEN1 (0.44) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL5847445 | 0.78 | PDK2 (0.32) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL30805720 | 0.77 | LMNA (0.47) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL5949152 | 0.77 | MEN1 (0.46) | MEN1KMT2ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102276514-B | Fluorene-bridged blue phosphorescent main body material and preparation method and application thereof | UNIV HUAZHONG SCIENCE TECH | 2014-01-15 | — | — | CN | disclosed |
| EP-1385919-A1 | SUBSTITUTED FLUORENE POLYMERS, THEIR PREPARATION AND USES | Cambridge Display Technology Limited (GB) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002092724-A1 | SUBSTITUTED FLUORENE POLYMERS, THEIR PREPARATION AND USES | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2002-11-21 | — | — | WO | disclosed |