Pyridine

Pyridine

SCHEMBL28107404

c1ccncc1.c1ncc2[nH]nnc2n1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.40
METAP1 P53582 1/20 0.40
TSHR P16473 1/20 0.32
NAPRT Q6XQN6 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrimidine SCHEMBL3822426 0.91 METAP2 (0.37) METAP2METAP1
SCHEMBL29356966 0.89
SCHEMBL26606 0.89
SCHEMBL2587704 0.89 METAP2 (0.35) METAP2METAP1
SCHEMBL30544002 0.87 METAP2 (0.34) METAP2METAP1
Hydrochloric Acid SCHEMBL5791474 0.87 METAP2 (0.34) METAP2METAP1
Cyclopentane SCHEMBL248218 0.83 METAP2 (0.33) METAP2METAP1
Phenazine SCHEMBL28258542 0.79 EGFR (0.43) METAP2METAP1
SCHEMBL19741076 0.79 METAP2 (0.30) METAP2METAP1
Sulfamide SCHEMBL9442883 0.79 METAP2 (0.30) METAP2METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555779-B The piperazine class of weeding 巴斯夫欧洲公司 2019-05-10 CN disclosed
CN-109414528-A Drug-coated balloon catheter for body lumens 优敦力公司 2019-03-01 CN disclosed
CN-109415738-A For the plant promoter of transgene expression and 3 ' UTR 美国陶氏益农公司 2019-03-01 CN disclosed
CN-108513583-A Recombinant maize B chromosome sequences and uses thereof 孟山都技术公司 2018-09-07 CN disclosed
CN-108309385-A Lung volume reduction compression implant structure in the air flue that torque mitigates 纽姆克斯股份有限公司 2018-07-24 CN disclosed
CN-107739737-A Method and composition for Weeds distribution 孟山都技术公司 2018-02-27 CN disclosed
CN-107454821-A Weaken the phytotoxicity of multidigit point fungicide by high molecular weight dispersant 巴斯夫欧洲公司 2017-12-08 CN disclosed
CN-103957697-B Methods and compositions for weed control 孟山都技术公司 2017-10-24 CN disclosed
CN-107099548-A The method for improving transformation of soybean efficiency 北京大北农生物技术有限公司 2017-08-29 CN disclosed
CN-104602528-B Herbicidal combinations comprising 4 amino, 3 chlorine 5 fluorine 6 (methoxyphenyl of 4 chlorine, 2 fluorine 3) formic acid of pyridine 2 or derivatives thereof and triazolopyrimidine sulfonamide 美国陶氏益农公司 2017-07-04 CN disclosed
CN-106755061-A Use the method for transformation of sulfonylurea herbicide hydrolase gene alternatively label 北京大北农科技集团股份有限公司 2017-05-31 CN disclosed
CN-106755062-A Use the method for transformation of sulfonylurea herbicide hydrolase gene alternatively label 北京大北农科技集团股份有限公司 2017-05-31 CN disclosed
CN-106661002-A Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases 纽韦卢森公司 2017-05-10 CN disclosed
CN-106573899-A Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases 纽韦卢森公司 2017-04-19 CN disclosed
CN-103929962-B Comprise the compositions of active component, oil and ionic liquid 巴斯夫欧洲公司 2016-12-07 CN disclosed
CN-106164039-A Derived from the side chain of plant source and the polycarboxylic alkyl ester of straight chain alcohol and Arrcostab purposes in agrochemical formulations 科莱恩私人控股公司 2016-11-23 CN disclosed