Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamide SCHEMBL9442883 | 0.89 | METAP2 (0.30) | METAP2METAP1 | |
| SCHEMBL2587704 | 0.89 | METAP2 (0.35) | METAP2METAP1 | |
| SCHEMBL26606 | 0.89 | — | — | |
| SCHEMBL29356966 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL5791474 | 0.87 | METAP2 (0.34) | METAP2METAP1 | |
| SCHEMBL30544002 | 0.87 | METAP2 (0.34) | METAP2METAP1 | |
| Cyclopentane SCHEMBL248218 | 0.83 | METAP2 (0.33) | METAP2METAP1 | |
| Pyrimidine SCHEMBL3822426 | 0.80 | METAP2 (0.37) | METAP2METAP1 | |
| Benzenesulfonamide SCHEMBL15816975 | 0.79 | CA1 (0.44) | — | |
| Pyridine SCHEMBL28107404 | 0.79 | METAP2 (0.40) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221128-B2 | Intermediate of preparing high-purity sulfonamide compound | ORIENTAL (LUZHOU) AGROCHEMICALS. CO., LTD. (CN) | 2019-03-05 | — | — | US | disclosed |
| US-20180201574-A1 | INTERMEDIATE OF PREPARING HIGH-PURITY SULFONAMIDE COMPOUND | ORIENTAL (LUZHOU) AGROCHEMICALS. CO., LTD. (CN) | 2018-07-19 | — | — | US | disclosed |
| US-9950997-B2 | Method for preparing high-purity sulfonamide compound, and intermediate of sulfonamide compound | ORIENTAL LUZHOU AGROCHEMICALS CO LTD (CN) | 2018-04-24 | — | — | US | disclosed |
| US-20170369429-A1 | METHOD FOR PREPARING HIGH-PURITY SULFONAMIDE COMPOUND, AND INTERMEDIATE OF SULFONAMIDE COMPOUND | ORIENTAL (LUZHOU) AGROCHEMICALS CO LTD (CN) | 2017-12-28 | — | — | US | disclosed |
| CN-103923086-B | A kind of preparation method of 5-alkoxyl-1,2,4-triazole [4,3-c] pyrimidine-3 (2H)-thioketone | 齐鲁工业大学 | 2016-08-31 | — | — | CN | disclosed |
| CN-102617577-A | Preparation method of triazolopyrimidine sulfonyl chloride type compound | BEIJING NUTRICHEM INTERNAT TRADE CO LTD | 2012-08-01 | — | — | CN | disclosed |
| CN-102617577-A | Preparation method of triazolopyrimidine sulfonyl chloride type compound | BEIJING NUTRICHEM INTERNAT TRADE CO LTD | 2012-08-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10221128-B2 | Intermediate of preparing high-purity sulfonamide compound | STS, SULT1A1, SULT2A1 | METAP2 3345/4885METAP1 4250/4885CDC25B 1139/4885 |
| US-20170369429-A1 | METHOD FOR PREPARING HIGH-PURITY SULFONAMIDE COMPOUND, AND INTERMEDIATE OF SULFONAMIDE COMPOUND | STS, SULT1A1, SRM | METAP2 3067/4885METAP1 4171/4885CDC25B 1043/4885 |
| US-20180201574-A1 | INTERMEDIATE OF PREPARING HIGH-PURITY SULFONAMIDE COMPOUND | STS, SULT1A1, SULT2A1 | METAP2 3345/4885METAP1 4250/4885CDC25B 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.