Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356966 | 0.94 | — | — | |
| SCHEMBL2587704 | 0.94 | METAP2 (0.35) | METAP2METAP1 | |
| SCHEMBL26606 | 0.94 | — | — | |
| SCHEMBL30544002 | 0.92 | METAP2 (0.34) | METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL5791474 | 0.92 | METAP2 (0.34) | METAP2METAP1 | |
| Piperidine SCHEMBL28232867 | 0.91 | ALDH1A1 (0.30) | — | |
| Pyrimidine SCHEMBL3822426 | 0.85 | METAP2 (0.37) | METAP2METAP1 | |
| Pyridine SCHEMBL28107404 | 0.83 | METAP2 (0.40) | METAP2METAP1 | |
| Sulfamide SCHEMBL9442883 | 0.83 | METAP2 (0.30) | METAP2METAP1 | |
| Phenazine SCHEMBL28258542 | 0.80 | EGFR (0.43) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157907-B1 | PROCESS FOR THE PREPARATION OF TRIAZOLO[4,5-D]PYRIMIDINE CYCLOPENTANE COMPOUNDS | FLAMMA SPA (IT) | 2018-08-29 | — | — | EP | claimed |
| US-10011605-B2 | Process for the preparation of triazolo[4,5-D] pyrimidine cyclopentane compounds | FLAMMA SPA (IT) | 2018-07-03 | — | — | US | claimed |
| US-20170129898-A1 | PROCESS FOR THE PREPARATION OF TRIAZOLO[4,5-D] PYRIMIDINE CYCLOPENTANE COMPOUNDS | FLAMMA SPA (IT) | 2017-05-11 | — | — | US | claimed |
| EP-3157907-A1 | PROCESS FOR THE PREPARATION OF TRIAZOLO[4,5-D]PYRIMIDINE CYCLOPENTANE COMPOUNDS | Flamma S.P.A. (IT) | 2017-04-26 | — | — | EP | claimed |
| WO-2015193165-A1 | PROCESS FOR THE PREPARATION OF TRIAZOLO[4,5-D] PYRIMIDINE CYCLOPENTANE COMPOUNDS | FLAMMA SPA (IT) | 2015-12-23 | — | — | WO | claimed |
| EP-2480330-B1 | A PROCESS AND CATALYST FOR THE CATALYTIC HYDROGENATION OF AROMATIC AND HETEROAROMATIC NITRO COMPOUNDS | ASTRAZENECA AB (SE) | 2021-05-26 | — | — | EP | disclosed |
| EP-3157907-B1 | PROCESS FOR THE PREPARATION OF TRIAZOLO[4,5-D]PYRIMIDINE CYCLOPENTANE COMPOUNDS | FLAMMA SPA (IT) | 2018-08-29 | — | — | EP | disclosed |
| US-10011605-B2 | Process for the preparation of triazolo[4,5-D] pyrimidine cyclopentane compounds | FLAMMA SPA (IT) | 2018-07-03 | — | — | US | disclosed |
| US-10011605-B2 | Process for the preparation of triazolo[4,5-D] pyrimidine cyclopentane compounds | FLAMMA SPA (IT) | 2018-07-03 | — | — | US | disclosed |
| US-10011605-B2 | Process for the preparation of triazolo[4,5-D] pyrimidine cyclopentane compounds | FLAMMA SPA (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180148745-A1 | HEMOPROTEIN CATALYSTS FOR IMPROVED ENANTIOSELECTIVE ENZYMATIC SYNTHESIS OF TICAGRELOR | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-05-31 | — | — | US | disclosed |
| EP-3303267-A2 | HEMOPROTEIN CATALYSTS FOR IMPROVED ENANTIOSELECTIVE ENZYMATIC SYNTHESIS OF TICAGRELOR | California Institute of Technology (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2011036479-A2 | PROCESS AND CATALYST | ASTRAZENECA AB (SE) | 2011-03-31 | — | — | WO | disclosed |
| US-20110071290-A1 | Process And Catalyst | ASTRAZENECA AB (SE) | 2011-03-24 | — | — | US | disclosed |
| US-20100324289-A1 | Chemical Process | ASTRAZENECA AB (SE) | 2010-12-23 | — | — | US | disclosed |
| US-7799914-B2 | Chemical process | ASTRAZENECA AB (SE) | 2010-09-21 | — | — | US | disclosed |
| US-7393962-B2 | Chemical process | ASTRAZENECA AB (SE) | 2008-07-01 | — | — | US | disclosed |
| US-20070219371-A1 | Chemical Process | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | US | disclosed |
| US-20070197805-A1 | Chemical process | ASTRAZENECA AB (SE) | 2007-08-23 | — | — | US | disclosed |
| EP-1732916-B1 | PROCESS FOR THE PREPARATION OF ALKOXYCARBONYLMETHOXY-CYCLOPENTANES | ASTRAZENECA AB (SE) | 2007-07-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197805-A1 | Chemical process | CBR3, CYP4F3, NOX3 | METAP2 4224/4885METAP1 4089/4885 |
| US-20070219371-A1 | Chemical Process | ADH1C, ADH1A, CBR1 | METAP2 3883/4885METAP1 3336/4885 |
| US-20100324289-A1 | Chemical Process | CBR1, CYP2E1, ADH1C | METAP2 3698/4885METAP1 2949/4885 |
| US-20110071290-A1 | Process And Catalyst | PPOX, NOX5, NUDT1 | METAP2 1061/4885METAP1 964/4885 |
| US-10011605-B2 | Process for the preparation of triazolo[4,5-D] pyrimidine cyclopentane compounds | TBXA2R, THPO, P2RY4 | METAP2 3632/4885METAP1 3251/4885 |
| US-20170129898-A1 | PROCESS FOR THE PREPARATION OF TRIAZOLO[4,5-D] PYRIMIDINE CYCLOPENTANE COMPOUNDS | TBXA2R, THPO, P2RY4 | METAP2 3632/4885METAP1 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.