Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358584 | 0.83 | CES2 (0.41) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL4253407 | 0.80 | CES2 (0.38) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL4253413 | 0.80 | CES2 (0.38) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL30447270 | 0.75 | HTT (0.34) | CES2CES1ALDH1A1KMT2AHSD11B1 | |
| SCHEMBL8595697 | 0.74 | GRIK1 (0.44) | CES2CES1TSHRALDH1A1GRIK1 | |
| SCHEMBL111090 | 0.74 | GRIK1 (0.44) | CES2CES1TSHRALDH1A1GRIK1 | |
| SCHEMBL36412 | 0.74 | GRIK1 (0.44) | CES2CES1TSHRALDH1A1GRIK1 | |
| SCHEMBL1244582 | 0.74 | GRIK1 (0.44) | CES2CES1TSHRALDH1A1GRIK1 | |
| SCHEMBL1245246 | 0.74 | GRIK1 (0.44) | CES2CES1TSHRALDH1A1GRIK1 | |
| SCHEMBL643109 | 0.74 | GRIK1 (0.44) | CES2CES1TSHRALDH1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103313853-B | Laminate | F顾问株式会社 | 2016-10-12 | — | — | CN | disclosed |