Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28318500 | 0.86 | KMT2A (0.38) | MAOBKMT2AMEN1NPC1KDM4E | |
| SCHEMBL28107677 | 0.77 | HSD17B10 (0.44) | KMT2AMEN1NPC1KDM4EMAPT | |
| SCHEMBL28107671 | 0.71 | L3MBTL1 (0.43) | KMT2AMEN1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL21167123 | 0.71 | GSTP1 (0.44) | MAOBNPC1MAPTRAB9AGAA | |
| SCHEMBL29665126 | 0.70 | CYP2A6 (0.60) | MAOBKMT2AMEN1NPC1KDM4E | |
| SCHEMBL1207986 | 0.70 | CYP2A6 (0.60) | MAOBKMT2AMEN1NPC1KDM4E | |
| SCHEMBL12083558 | 0.69 | KDM4E (0.47) | KMT2AMEN1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL15197465 | 0.69 | CYP2A6 (0.58) | MAOBKMT2AMEN1NPC1KDM4E | |
| SCHEMBL15197478 | 0.69 | CYP2A6 (0.58) | MAOBKMT2AMEN1NPC1KDM4E | |
| SCHEMBL28107380 | 0.68 | CHEK1 (0.41) | KMT2AMEN1KDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | disclosed |