Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22544312 | 0.87 | HSD17B10 (0.53) | HSD17B10RXRARXRBGPR3TOP2A | |
| SCHEMBL28107376 | 0.83 | L3MBTL1 (0.51) | HSD17B10L3MBTL1KMT2AHPGDNPC1 | |
| SCHEMBL28319588 | 0.82 | HSD17B10 (0.46) | HSD17B10GPR3TOP2AKMT2AHPGD | |
| SCHEMBL28107676 | 0.82 | HSD17B10 (0.46) | HSD17B10RXRARXRBGPR3TOP2A | |
| SCHEMBL28107378 | 0.82 | HSD17B10 (0.46) | HSD17B10RXRARXRBGPR3TOP2A | |
| SCHEMBL28107672 | 0.82 | HSD17B10 (0.46) | HSD17B10RXRARXRBGPR3TOP2A | |
| SCHEMBL28107372 | 0.79 | HSD17B10 (0.43) | HSD17B10RXRARXRBGPR3TOP2A | |
| SCHEMBL21167123 | 0.77 | GSTP1 (0.44) | RXRARXRBL3MBTL1HTR1DNPC1 | |
| SCHEMBL28107673 | 0.77 | MAOB (0.36) | KMT2AHTR1DHSD17B1HSD17B2NPC1 | |
| SCHEMBL28107373 | 0.77 | CYP2A6 (0.47) | HSD17B10RXRARXRBGPR3TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | disclosed |