Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28107376 | 0.87 | L3MBTL1 (0.51) | L3MBTL1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL28835460 | 0.86 | AURKA (0.51) | L3MBTL1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL28107676 | 0.81 | HSD17B10 (0.46) | L3MBTL1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL28107380 | 0.81 | CHEK1 (0.41) | KDM4EALDH1A1MAPTHTTMEN1 | |
| SCHEMBL22544312 | 0.75 | HSD17B10 (0.53) | L3MBTL1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL22499359 | 0.74 | KDM4E (0.55) | L3MBTL1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL28723366 | 0.72 | RET (0.44) | L3MBTL1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL28107673 | 0.71 | MAOB (0.36) | KDM4EMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28107672 | 0.71 | HSD17B10 (0.46) | L3MBTL1ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL28107378 | 0.71 | HSD17B10 (0.46) | KDM4EALDH1A1HPGDMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117113-B | Polysubstituted carbazole, derivative and its synthetic method | 湘潭大学 | 2019-08-16 | — | — | CN | disclosed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | disclosed |