Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892213 | 0.86 | RORC (0.33) | RORC | |
| SCHEMBL16892204 | 0.86 | RORC (0.33) | RORC | |
| SCHEMBL16887644 | 0.83 | RORC (0.32) | RORC | |
| SCHEMBL16887663 | 0.83 | RORC (0.32) | RORC | |
| SCHEMBL28243436 | 0.75 | EPHX2 (0.33) | — | |
| SCHEMBL2931908 | 0.74 | APLNR (0.32) | — | |
| SCHEMBL16224739 | 0.72 | APLNR (0.31) | — | |
| SCHEMBL28107803 | 0.71 | POLB (0.30) | — | |
| SCHEMBL9044471 | 0.71 | CYP4F2 (0.35) | — | |
| SCHEMBL383185 | 0.69 | NR1H2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061971-B | Pyrrolidinyl sulfone derivatives and their use as ROR gamma modulators | 百时美施贵宝公司 | 2019-03-12 | — | — | CN | disclosed |
| CN-106061971-A | Pyrrolidinyl sulfone derivatives and their use as ROR gamma modulators | 百时美施贵宝公司 | 2016-10-26 | — | — | CN | disclosed |