Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931908 | 0.77 | APLNR (0.32) | — | |
| SCHEMBL5567581 | 0.73 | — | — | |
| SCHEMBL16224739 | 0.71 | APLNR (0.31) | — | |
| SCHEMBL16875169 | 0.71 | FKBP1A (0.31) | — | |
| SCHEMBL28107802 | 0.71 | RORC (0.34) | — | |
| SCHEMBL31396189 | 0.71 | — | — | |
| SCHEMBL31074264 | 0.71 | — | — | |
| SCHEMBL52124 | 0.69 | APLNR (0.34) | — | |
| SCHEMBL25832210 | 0.69 | APLNR (0.34) | — | |
| SCHEMBL4043463 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061971-B | Pyrrolidinyl sulfone derivatives and their use as ROR gamma modulators | 百时美施贵宝公司 | 2019-03-12 | — | — | CN | disclosed |
| CN-106061971-A | Pyrrolidinyl sulfone derivatives and their use as ROR gamma modulators | 百时美施贵宝公司 | 2016-10-26 | — | — | CN | disclosed |