Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057456 | 0.79 | NPC1 (0.46) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL12431653 | 0.77 | NFE2L2 (0.36) | MAPTMEN1KMT2ACSNK2A1ALDH1A1 | |
| SCHEMBL11733174 | 0.76 | RAB9A (0.46) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL11581911 | 0.76 | RAB9A (0.33) | MEN1KMT2AALDH1A1LMNARAB9A | |
| SCHEMBL11726779 | 0.76 | SMN1; SMN2 (0.35) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL27509106 | 0.74 | RAB9A (0.33) | MEN1KMT2AALDH1A1LMNARAB9A | |
| SCHEMBL11317412 | 0.73 | ACHE (0.50) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL7247293 | 0.73 | MCL1 (0.43) | PTGS1PTGS2 | |
| Methane SCHEMBL17822408 | 0.73 | CSNK2A1 (0.41) | MEN1KMT2ACSNK2A1ALDH1A1LMNA | |
| SCHEMBL21872427 | 0.72 | NFE2L2 (0.36) | MAPTMEN1KMT2ANFE2L2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132934-B | The benzimidizole derivatives and its medical composition for treating inflammatory conditions | 加拉帕戈斯股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-106132934-A | The benzimidizole derivatives for the treatment of inflammatory disease and medical composition thereof | 加拉帕戈斯股份有限公司 | 2016-11-16 | — | — | CN | disclosed |