Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 11/20 | 0.96 |
| ▸ | METAP1 | P53582 | 8/20 | 0.96 |
| ▸ | NPC1 | O15118 | 6/20 | 0.96 |
| ▸ | RAB9A | P51151 | 6/20 | 0.96 |
| ▸ | PKM | P14618 | 5/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.96 |
| ▸ | LMNA | P02545 | 3/20 | 0.96 |
| ▸ | HPGD | P15428 | 2/20 | 0.96 |
| ▸ | MTOR | P42345 | 1/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | CBFB | Q13951 | 9/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484592 | 0.98 | METAP2 (1.00) | METAP2METAP1NPC1RAB9APKM | |
| SCHEMBL29484603 | 0.98 | METAP2 (1.00) | METAP2METAP1NPC1RAB9APKM | |
| SCHEMBL29405601 | 0.98 | METAP2 (1.00) | METAP2METAP1NPC1RAB9APKM | |
| SCHEMBL124947 | 0.98 | METAP2 (1.00) | METAP2METAP1NPC1RAB9APKM | |
| Hydrochloric Acid SCHEMBL2147494 | 0.96 | METAP2 (0.96) | METAP2METAP1NPC1RAB9APKM | |
| SCHEMBL9338775 | 0.96 | METAP2 (0.96) | METAP2METAP1NPC1RAB9APKM | |
| SCHEMBL28168903 | 0.96 | METAP2 (0.96) | METAP2METAP1NPC1RAB9APKM | |
| SCHEMBL28003516 | 0.95 | METAP2 (0.93) | METAP2METAP1NPC1RAB9APKM | |
| SCHEMBL4808230 | 0.88 | METAP2 (0.81) | METAP2METAP1NPC1RAB9APKM | |
| Hydrochloric Acid SCHEMBL4812284 | 0.87 | METAP2 (0.79) | METAP2METAP1NPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008564-A | Cage 2-(2-pyridyl)benzimidazole zinc complex, preparation method and application thereof | 山西大学 | 2016-10-12 | — | — | CN | disclosed |
| CN-106008564-A | Cage 2-(2-pyridyl)benzimidazole zinc complex, preparation method and application thereof | 山西大学 | 2016-10-12 | — | — | CN | disclosed |