Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28109712 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHPGDALDH1A1POLB | |
| SCHEMBL28109708 | 0.88 | PDE4A (0.50) | SMN1; SMN2LMNAHPGDALDH1A1TP53 | |
| SCHEMBL28110177 | 0.83 | PDE4B (0.57) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL28531912 | 0.74 | HDAC6 (0.80) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28109719 | 0.69 | HDAC3 (0.64) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL3048584 | 0.68 | HPGD (0.43) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL3946668 | 0.67 | HSP90AA1 (0.46) | SMN1; SMN2LMNAALDH1A1POLBPDE4A | |
| SCHEMBL28109706 | 0.67 | L3MBTL1 (0.45) | SMN1; SMN2LMNARXFP1ALDH1A1POLB | |
| SCHEMBL16202036 | 0.67 | ALDH1A1 (0.52) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL16641094 | 0.66 | CYP19A1 (0.77) | ALDH1A1POLBHSP90AA1ABCB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061975-A | Pyrazolo[1,5-a]pyrimidines as antiviral compounds | 阿波德穆斯公司 | 2016-10-26 | — | — | CN | claimed |
| CN-106061975-B | Pyrazolo [1,5-A] pyrimidine as antiviral compound | 库洛维公司 | 2019-09-24 | — | — | CN | disclosed |
| CN-106061975-A | Pyrazolo[1,5-a]pyrimidines as antiviral compounds | 阿波德穆斯公司 | 2016-10-26 | — | — | CN | disclosed |