Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CDH1 | P12830 | 1/20 | 0.49 |
| ▸ | APC | P25054 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267266 | 1.00 | KDM4E (0.56) | KDM4EGAAL3MBTL1LMNAPKM | |
| SCHEMBL6262638 | 0.88 | KDM4E (0.71) | KDM4EGAAL3MBTL1LMNAPKM | |
| SCHEMBL11263581 | 0.86 | KDM4E (0.72) | KDM4EGAAL3MBTL1LMNAPKM | |
| SCHEMBL28110238 | 0.86 | KDM4E (0.72) | KDM4EGAAL3MBTL1LMNAPKM | |
| SCHEMBL14416952 | 0.84 | KDM4E (0.79) | KDM4EGAAL3MBTL1LMNAPKM | |
| SCHEMBL3593759 | 0.82 | KMT2A (0.67) | KDM4EGAAL3MBTL1LMNAPKM | |
| SCHEMBL11403339 | 0.81 | KDM4E (0.50) | KDM4EGAAL3MBTL1LMNAPKM | |
| SCHEMBL28118425 | 0.80 | ALDH1A1 (0.77) | KDM4EGAAL3MBTL1LMNAALDH1A1 | |
| SCHEMBL29581721 | 0.80 | HSD17B10 (0.53) | KDM4ELMNACDH1APCCTNNB1 | |
| SCHEMBL6109697 | 0.80 | HSD17B10 (0.53) | KDM4ELMNACDH1APCCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243048-B | A kind of hydrazone compounds and the preparation method and application thereof of the structure of benzopyrazines containing chlorine | 浙江工业大学 | 2019-01-15 | — | — | CN | claimed |
| CN-106243048-A | A kind of hydrazone compounds of chloride benzopyrazines structure and preparation method and application | 浙江工业大学 | 2016-12-21 | — | — | CN | claimed |
| CN-106243048-B | A kind of hydrazone compounds and the preparation method and application thereof of the structure of benzopyrazines containing chlorine | 浙江工业大学 | 2019-01-15 | — | — | CN | disclosed |
| CN-106172418-B | A kind of application of hydrazone compounds of the structure of benzopyrazines containing chlorine as fungicide | 浙江工业大学 | 2018-11-13 | — | — | CN | disclosed |
| CN-106243048-A | A kind of hydrazone compounds of chloride benzopyrazines structure and preparation method and application | 浙江工业大学 | 2016-12-21 | — | — | CN | disclosed |
| CN-106172418-A | The hydrazone compounds of a kind of chloride benzopyrazines structure is as the application of antibacterial | 浙江工业大学 | 2016-12-07 | — | — | CN | disclosed |