Benzotriazole

Benzotriazole

SCHEMBL28110368

CCCCCCCC[PH](C)(CCCCCCCC)CCCCCCCC.c1ccc2[nH]nnc2c1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 4/20 0.40
CYP4Z1 Q86W10 4/20 0.38
SPHK2 Q9NRA0 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
BCHE P06276 1/20 0.36
TRPC3 Q13507 1/20 0.36
TRPC4 Q9UBN4 1/20 0.36
TRPC5 Q9UL62 1/20 0.36
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
DAGLA Q9Y4D2 1/20 0.34
ASAH1 Q13510 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dodecane SCHEMBL28270228 0.91 SLC9A1 (0.46) SLC9A1CYP4Z1SPHK2SPHK1NPC1
Benzotriazole SCHEMBL5672261 0.88 SLC9A1 (0.38) SLC9A1CYP4Z1SPHK2SPHK1NPC1
Octadecylamine SCHEMBL9978545 0.86 TLR8 (0.45) SLC9A1ALDH1A1
Dodecylamine SCHEMBL27579317 0.86 TLR8 (0.45) SLC9A1ALDH1A1
Benzotriazole SCHEMBL5671794 0.84 RAB9A (0.38) SLC9A1CYP4Z1NPC1RAB9ABCHE
Benzotriazole SCHEMBL27636530 0.84 ASAH1 (0.40) SLC9A1CYP4Z1SPHK2SPHK1NPC1
Benzotriazole SCHEMBL28156804 0.83 SLC9A1 (0.41) SLC9A1CYP4Z1SPHK2SPHK1NPC1
Benzotriazole SCHEMBL8653869 0.83 BCHE (0.39) SLC9A1CYP4Z1NPC1RAB9ABCHE
Benzotriazole SCHEMBL27760955 0.82 SLC9A1 (0.47) SLC9A1CYP4Z1SPHK2SPHK1ASAH1
Benzotriazole SCHEMBL5194661 0.82 DDAH1 (0.41) SLC9A1NPC1RAB9ABCHETRPC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106103569-A Nitrile copolymer rubber composition 日本瑞翁株式会社 2016-11-09 CN disclosed