Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 14/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.52 |
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | USP2 | O75604 | 6/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775247 | 0.85 | ALDH1A1 (0.46) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8776077 | 0.84 | MAOA (0.44) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL17653985 | 0.83 | MEN1 (0.48) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30900832 | 0.83 | MEN1 (0.48) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7167304 | 0.81 | TLR8 (0.51) | MAOAMAOBALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8776831 | 0.81 | ALDH1A1 (0.49) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8775356 | 0.79 | SMN1; SMN2 (0.47) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8776753 | 0.79 | MAOA (0.43) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8775539 | 0.79 | L3MBTL1 (0.47) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27746869 | 0.78 | NPC1 (0.61) | ALDH1A1CYP1A2SMN1; SMN2KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125985-A | Method for preparing quinazolinone by activating alkylbenzene benzyl site C (sp 3) -H bond by photo-generated chlorine free radical | 桂林理工大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-112941549-A | Synthetic method of quinazoline derivative, benzoxazine derivative and benzothiazole derivative | 石河子大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-109879820-A | A kind of synthetic method of quinazolinone heterocyclic compound | 扬州大学 | 2019-06-14 | — | — | CN | disclosed |
| CN-106008370-B | A kind of synthetic method of 2- substituted quinazoline heterocyclic compounds | 温州大学 | 2018-12-18 | — | — | CN | disclosed |
| CN-106008370-A | Synthesis method for 2-substituted quinazoline heterocyclic compound | 温州大学 | 2016-10-12 | — | — | CN | disclosed |