Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24858087 | 0.89 | — | — | |
| SCHEMBL10527013 | 0.83 | NPSR1 (0.38) | ALDH1A1SMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL15506868 | 0.80 | NPSR1 (0.39) | ALDH1A1SMN1; SMN2HDAC3HDAC1HDAC2 | |
| Carbamic Acid SCHEMBL28572811 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2HDAC3HDAC1HDAC2 | |
| Methyl Carbamate SCHEMBL11664166 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL10527009 | 0.79 | HDAC3 (0.33) | ALDH1A1SMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL11660318 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2APOLB | |
| Cyclohexane SCHEMBL13506634 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL24572117 | 0.76 | RORC (0.39) | MEN1KMT2A | |
| SCHEMBL26018305 | 0.76 | RORC (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110042099-A | RNA in skin and fibrotic conditions is interfered | 菲奥医药公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-105131067-B | RNA in skin and fibrotic conditions is interfered | 雷克西制药公司 | 2019-02-19 | — | — | CN | disclosed |
| CN-106074591-A | RNA interference in eye disease | 雷克西制药公司 | 2016-11-09 | — | — | CN | disclosed |