SCHEMBL2811061

SCHEMBL2811061

CC(=COc1cccc(C)c1)C(=Nc1ccccc1)Sc1cccc(C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
HTR3E A5X5Y0 2/20 0.33
HTR3B O95264 2/20 0.33
HTR3A P46098 2/20 0.33
HTR3D Q70Z44 2/20 0.33
HTR3C Q8WXA8 2/20 0.33
ACHE P22303 1/20 0.33
CRHR1 P34998 1/20 0.32
TERT O14746 1/20 0.32
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MAPT P10636 1/20 0.32
IDE P14735 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12851010 1.00 LMNA (0.35) LMNAHTR3EHTR3BHTR3AHTR3D
SCHEMBL2811058 1.00 LMNA (0.35) LMNAHTR3EHTR3BHTR3AHTR3D
SCHEMBL2811617 0.96 LMNA (0.35) LMNAHTR3EHTR3BHTR3AHTR3D
SCHEMBL12851040 0.96 LMNA (0.35) LMNAHTR3EHTR3BHTR3AHTR3D
SCHEMBL2811621 0.96 LMNA (0.35) LMNAHTR3EHTR3BHTR3AHTR3D
SCHEMBL2809297 0.96 HTR3E (0.33) LMNAHTR3EHTR3BHTR3AHTR3D
SCHEMBL2809296 0.96 HTR3E (0.33) LMNAHTR3EHTR3BHTR3AHTR3D
SCHEMBL12850904 0.96 HTR3E (0.33) LMNAHTR3EHTR3BHTR3AHTR3D
SCHEMBL2807554 0.93 ACHE (0.38) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL12851094 0.93 ACHE (0.38) HTR3EHTR3BHTR3AHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278473-B2 Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-23 US disclosed
WO-2009064031-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME OXER1, CBR1, DEGS1 LMNA 2201/4885HTR3E 3827/4885HTR3B 4065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.