SCHEMBL28110666

SCHEMBL28110666

CC(C)(C)c1ccc2c(c1)Nc1ccc(C(C)(C)C)cc1S2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 13/20 0.58
CYBB P04839 2/20 0.58
NOX3 Q9HBY0 2/20 0.58
NOX4 Q9NPH5 2/20 0.58
MAPT P10636 6/20 0.44
GAA P10253 5/20 0.44
SNCA P37840 5/20 0.44
MAPK1 P28482 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALOX15 P16050 3/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30336020 0.93 SNCA (0.50) NOX1CYBBNOX3NOX4MAPT
SCHEMBL20664930 0.93 SNCA (0.50) NOX1CYBBNOX3NOX4MAPT
SCHEMBL25898787 0.88 NOX1 (0.71) NOX1CYBBNOX3NOX4MAPT
SCHEMBL1719191 0.88 NOX1 (0.62) NOX1CYBBNOX3NOX4MAPT
SCHEMBL10131237 0.79 SNCA (0.37) NOX1CYBBNOX3NOX4MAPT
SCHEMBL11375009 0.77 NOX1 (0.69) NOX1CYBBNOX3NOX4MAPT
SCHEMBL22673417 0.76 ALDH1A1 (0.44) NOX1CYBBNOX3NOX4MAPT
SCHEMBL28642307 0.76 ALDH1A1 (0.44) NOX1CYBBNOX3NOX4MAPT
SCHEMBL25372479 0.76 ALDH1A1 (0.44) MAPTGAANPC1RAB9AMEN1
SCHEMBL31027466 0.76 ALDH1A1 (0.44) MAPTGAANPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106242976-A It is the small molecule emitter material by body unit and preparation and application thereof based on 1,2 dibenzenyls 华南理工大学 2016-12-21 CN disclosed