SCHEMBL25898787

SCHEMBL25898787

CC(C)(C)c1ccc2c(c1)Nc1ccccc1S2

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 13/20 0.71
CYBB P04839 2/20 0.71
NOX3 Q9HBY0 2/20 0.71
NOX4 Q9NPH5 2/20 0.71
GAA P10253 8/20 0.59
MAPT P10636 8/20 0.59
MEN1 O00255 5/20 0.59
KMT2A Q03164 5/20 0.59
ALOX15 P16050 3/20 0.59
SNCA P37840 3/20 0.59
TDP1 Q9NUW8 3/20 0.59
BCHE P06276 2/20 0.59
ACHE P22303 2/20 0.59
CYP1A2 P05177 1/20 0.59
POLB P06746 1/20 0.59
CYP3A4 P08684 1/20 0.59
ADORA3 P0DMS8 1/20 0.59
ALOX12 P18054 1/20 0.59
MAOA P21397 1/20 0.59
CNR1 P21554 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1719191 0.90 NOX1 (0.62) NOX1CYBBNOX3NOX4GAA
SCHEMBL28110666 0.88 NOX1 (0.58) NOX1CYBBNOX3NOX4GAA
SCHEMBL7765548 0.85 NOX1 (0.65) NOX1CYBBNOX3NOX4GAA
Phenothiazine SCHEMBL4288768 0.84 ALOX15 (0.58) NOX1CYBBNOX3NOX4GAA
SCHEMBL9671163 0.83 NOX1 (0.61) NOX1CYBBNOX3NOX4GAA
SCHEMBL560225 0.83 NOX1 (1.00) NOX1CYBBNOX3NOX4GAA
Phenothiazine SCHEMBL6532335 0.83 NOX1 (1.00) NOX1CYBBNOX3NOX4GAA
SCHEMBL29475150 0.83 NOX1 (1.00) NOX1CYBBNOX3NOX4GAA
SCHEMBL22960498 0.82 NOX1 (0.62) NOX1CYBBNOX3NOX4GAA
Phenothiazine SCHEMBL28572162 0.81 NOX1 (0.57) NOX1CYBBNOX3NOX4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM NOX1 1733/4885CYBB 1969/4885NOX3 1811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.