Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Carbamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL2497041 | 0.96 | — | — | |
| Urea SCHEMBL27566105 | 0.87 | — | — | |
| Bicarbonate SCHEMBL10451074 | 0.87 | CA1 (0.56) | ACHECA1CA2CA9ALDH1A1 | |
| Bicarbonate SCHEMBL5154473 | 0.87 | — | — | |
| Benzene SCHEMBL28874592 | 0.85 | ACHE (0.50) | ACHELDHALDHBALDH1A1LMNA | |
| Bicarbonate SCHEMBL28370178 | 0.83 | CA1 (0.42) | ACHECA1CA2CA9LDHA | |
| Bicarbonate SCHEMBL11728075 | 0.82 | — | — | |
| Bicarbonate SCHEMBL7628696 | 0.82 | — | — | |
| Bicarbonate SCHEMBL7118766 | 0.82 | — | — | |
| Bicarbonate SCHEMBL28321876 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103635551-B | Waterborne polyurethane coating compositions | 拜尔材料科学有限公司 | 2017-02-22 | — | — | CN | disclosed |