Benzene

Benzene

SCHEMBL28874592

N.NC(=O)O.O=CO.c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
TDP1 Q9NUW8 3/20 0.36
TSHR P16473 2/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36
PARP1 P09874 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LDHA P00338 1/20 0.35
LDHB P07195 1/20 0.35
ALDH1A1 P00352 4/20 0.33
MAPK1 P28482 1/20 0.33
LMNA P02545 1/20 0.33
OR51E2 Q9H255 1/20 0.33
FGFR4 P22455 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL2497041 0.89
Carbamic Acid SCHEMBL28110669 0.85 ACHE (0.58) ACHETDP1TSHRBLMPMP22
Benzene SCHEMBL17875587 0.84 ALDH1A1 (0.33) TDP1TSHRALDH1A1MAPK1
Benzene SCHEMBL27625212 0.84 ACHE (0.70) ACHETDP1TSHRPOLBCYP3A4
Benzene SCHEMBL28286894 0.83 LMNA (0.53) ACHETDP1TSHRPOLBCYP3A4
Benzene SCHEMBL27800886 0.81
Urea SCHEMBL3240508 0.81
Urea SCHEMBL27566105 0.81
Benzene SCHEMBL27797533 0.81 ALDH1A1 (0.32) TDP1ALDH1A1MAPK1
Benzene SCHEMBL2116421 0.80 ACHE (0.78) ACHETDP1TSHRPOLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109912427-A A kind of preparation and purposes of ammonium salt 合肥祥晨化工有限公司 2019-06-21 CN disclosed