SCHEMBL28110900

SCHEMBL28110900

[CH2]C(C)(C)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.43
ALDH1A1 P00352 2/20 0.42
POLB P06746 1/20 0.40
NR1H3 Q13133 1/20 0.39
TTR P02766 1/20 0.38
CES1 P23141 1/20 0.38
CYP1A2 P05177 1/20 0.38
EHMT2 Q96KQ7 1/20 0.38
EHMT1 Q9H9B1 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SCN2A Q99250 1/20 0.37
CHRM2 P08172 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30472938 0.81 CASP3 (0.46) CASP3ALDH1A1POLBTTRCES1
SCHEMBL2156119 0.81 CASP3 (0.46) CASP3ALDH1A1POLBTTRCES1
SCHEMBL3275912 0.77 CASP3 (0.43) CASP3ALDH1A1POLBTTRCES1
SCHEMBL19067757 0.77 CASP3 (0.43) CASP3ALDH1A1POLBTTRCES1
SCHEMBL9944717 0.77 CASP3 (0.43) CASP3ALDH1A1POLBTTRCES1
SCHEMBL13243417 0.77 NR1H3 (0.40) CASP3ALDH1A1POLBNR1H3TTR
SCHEMBL9190585 0.75 POLB (0.46) CASP3POLBCES1CYP1A2EHMT2
SCHEMBL23222939 0.75 ALDH1A1 (0.42) CASP3ALDH1A1CES1CHRM2
SCHEMBL8813029 0.74 CASP3 (0.41) CASP3ALDH1A1POLBTTRCES1
SCHEMBL4368833 0.74 ALDH1A1 (0.44) CASP3ALDH1A1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106146623-A The preparation of MTP-bi-axungia acyl-phosphatidylethanolamine derivative and application 江苏东南纳米材料有限公司 2016-11-23 CN disclosed