SCHEMBL28110975

SCHEMBL28110975

C=CC(=O)OC(C)COc1[c]cccc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.35
TSHR P16473 1/20 0.35
THRA P10827 1/20 0.31
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11512126 0.80 ADRB2 (0.43) THRBTSHRTHRAADRB2ADRB1
SCHEMBL20210771 0.79 THRB (0.32) THRBTSHRTHRAHCAR2
SCHEMBL181492 0.79 THRB (0.54) THRBTSHRADRB2ADRB1ADRB3
SCHEMBL27687258 0.78 THRB (0.34) THRBTSHRTHRAHCAR2
SCHEMBL28898619 0.77 THRB (0.33) THRBTSHRTHRA
SCHEMBL9854345 0.76 TSHR (0.43) THRBTSHR
SCHEMBL28099055 0.76 THRB (0.38) THRBTSHR
SCHEMBL14237494 0.75 GRM4 (0.33) TSHR
SCHEMBL10510296 0.74 MAPT (0.36) TSHRADRB2ADRB1ADRB3
SCHEMBL5040435 0.74 THRB (0.60) THRBTSHRTHRAHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106255926-B Method for manufacturing cleaning blade, image forming apparatus, and process cartridge 株式会社理光 2019-05-07 CN disclosed
CN-108603953-A Light diffusing agent, light-diffusing resin composition and formed body 三菱瓦斯化学株式会社 2018-09-28 CN disclosed
CN-108473606-A Hardening resin composition 日东电工株式会社 2018-08-31 CN disclosed
CN-106414525-A Photocurable resin composition 电化株式会社 2017-02-15 CN disclosed
CN-106255926-A Method for manufacturing cleaning blade, image forming apparatus, and process cartridge 株式会社理光 2016-12-21 CN disclosed