SCHEMBL5040435

SCHEMBL5040435

C=CC(=O)OCCOc1[c]cccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.60
TSHR P16473 7/20 0.44
ALDH1A1 P00352 5/20 0.44
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 1/20 0.44
CYP3A4 P08684 3/20 0.41
HPGD P15428 1/20 0.38
HCAR2 Q8TDS4 1/20 0.36
AKR1B10 O60218 2/20 0.34
AKR1B1 P15121 2/20 0.34
KDM4E B2RXH2 2/20 0.33
THRA P10827 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MAOB P27338 1/20 0.31
PTK2B Q14289 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27650428 0.80 THRB (0.58) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL9421001 0.79 THRB (0.53) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL6238419 0.78 JAK2 (0.33) ALDH1A1HPGDKDM4ESMN1; SMN2MAPK1
SCHEMBL5032141 0.78 THRB (0.42) THRBTSHRALDH1A1TP53KDM4E
SCHEMBL24465 0.77 THRB (0.38) THRBALDH1A1TP53HSD17B10CYP3A4
SCHEMBL34035 0.76 THRB (1.00) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL28230342 0.76 THRB (1.00) THRBTSHRALDH1A1TP53HIF1A
Bromide SCHEMBL31049797 0.74 THRB (0.97) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL27842581 0.74 THRB (0.97) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL6196145 0.74 KDM4E (0.41) TSHRALDH1A1HSD17B10HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1928941-A1 RESIN COMPOSITION FOR FORMING ULTRAVIOLET ABSORBING LAYER AND LAMINATE COMPRISING ULTRAVIOLET ABSORBING LAYER Nippon Shokubai Co.,Ltd. (JP) 2008-06-11 EP disclosed
WO-2007037501-A1 RESIN COMPOSITION FOR FORMING ULTRAVIOLET ABSORBING LAYER AND LAMINATE COMPRISING ULTRAVIOLET ABSORBING LAYER NIPPON SHOKUBAI CO., LTD. (JP) 2007-04-05 WO disclosed