SCHEMBL28111002

SCHEMBL28111002

OCc1cccc(CO)n1.[Ni]

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.52
PGK1 P00558 1/20 0.46
PGK2 P07205 1/20 0.46
HRH4 Q9H3N8 1/20 0.44
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
KCNH2 Q12809 3/20 0.42
NPSR1 Q6W5P4 1/20 0.41
MPO P05164 1/20 0.38
NOTUM Q6P988 2/20 0.36
ADORA2A P29274 1/20 0.36
CXCR4 P61073 1/20 0.35
HSD11B1 P28845 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486201 0.97 CCR1 (0.55) CCR1PGK1PGK2HRH4GRIN2D
SCHEMBL243652 0.85 CCR1 (0.44) CCR1PGK1PGK2HRH4GRIN2D
SCHEMBL16682539 0.85 CCR1 (0.44) CCR1PGK1PGK2HRH4GRIN2D
SCHEMBL29028968 0.85 CCR1 (0.44) CCR1PGK1PGK2HRH4GRIN2D
SCHEMBL942940 0.85 CCR1 (0.44) CCR1PGK1PGK2HRH4GRIN2D
SCHEMBL31098473 0.85 CCR1 (0.44) CCR1PGK1PGK2HRH4GRIN2D
SCHEMBL5104176 0.85 CCR1 (0.44) CCR1PGK1PGK2HRH4GRIN2D
SCHEMBL6983417 0.85 PGK1 (0.45) CCR1PGK1PGK2HRH4GRIN2D
SCHEMBL16588099 0.83 CCR1 (0.48) CCR1PGK1PGK2HRH4GRIN2D
Hydrochloric Acid SCHEMBL21814461 0.83 GRIN2D (0.45) CCR1PGK1PGK2HRH4GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106243015-B 2, 6-pyridinedimethanol nickel complex crystal and application thereof 合肥祥晨化工有限公司 2018-09-25 CN disclosed
CN-106243015-A 2, 6-pyridinedimethanol nickel complex crystal and application thereof 合肥祥晨化工有限公司 2016-12-21 CN disclosed