SCHEMBL243652

SCHEMBL243652

OCc1cccc(CBr)n1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.44
PGK1 P00558 1/20 0.40
PGK2 P07205 1/20 0.40
KCNH2 Q12809 4/20 0.39
HRH4 Q9H3N8 1/20 0.39
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
MPO P05164 1/20 0.35
ADORA2A P29274 1/20 0.33
NOTUM Q6P988 1/20 0.33
HSD11B1 P28845 1/20 0.32
CXCR4 P61073 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245158 0.87 CCR1 (0.55) CCR1PGK1PGK2KCNH2HRH4
SCHEMBL486201 0.87 CCR1 (0.55) CCR1PGK1PGK2KCNH2HRH4
Bromide SCHEMBL1259355 0.85 CCR1 (0.52) CCR1PGK1PGK2KCNH2HRH4
SCHEMBL29811249 0.76
SCHEMBL16682539 0.76 CCR1 (0.44) CCR1PGK1PGK2KCNH2HRH4
SCHEMBL29028968 0.76 CCR1 (0.44) CCR1PGK1PGK2KCNH2HRH4
SCHEMBL6983417 0.76 PGK1 (0.45) CCR1PGK1PGK2KCNH2HRH4
SCHEMBL5104176 0.76 CCR1 (0.44) CCR1PGK1PGK2KCNH2HRH4
SCHEMBL942940 0.76 CCR1 (0.44) CCR1PGK1PGK2KCNH2HRH4
SCHEMBL31098473 0.76 CCR1 (0.44) CCR1PGK1PGK2KCNH2HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113564598-B Copper-titanium corrosive liquid for integrated circuit and production process thereof 江阴润玛电子材料股份有限公司 2023-06-13 CN claimed
CN-113564598-A Copper-titanium corrosive liquid for integrated circuit and production process thereof 江阴润玛电子材料股份有限公司 2021-10-29 CN claimed
JP-4537315-B2 2010-09-01 JP claimed
US-7666863-B2 Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases VIROPHARMA INCORPORATED (US) 2010-02-23 US claimed
US-20070231318-A1 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES SAHA ASHIS K 2007-10-04 US claimed
EP-1581207-A4 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INC (US) 2007-07-25 EP claimed
EP-1746888-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES Viropharma Incorporated (US) 2007-01-31 EP claimed
JP-2006510736-A 2006-03-30 JP claimed
WO-2005112640-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INCORPORATED (US) 2005-12-01 WO claimed
EP-1581207-A2 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES Viropharma Incorporated (US) 2005-10-05 EP claimed
US-20040162318-A1 Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases VIROPHARMA INCORPORATED 2004-08-19 US claimed
WO-2004041201-A2 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INCORPORATED (US) 2004-05-21 WO claimed
US-12241902-B2 Probes for detection of copper THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-03-04 US disclosed
CN-115108976-B Method for preparing pyridine carboxamide by one-step oxidation amidation 大连理工大学 2023-10-24 CN disclosed
CN-113564598-B Copper-titanium corrosive liquid for integrated circuit and production process thereof 江阴润玛电子材料股份有限公司 2023-06-13 CN disclosed
CN-115108976-A Method for preparing pyridine carboxamide through one-step oxidative amidation 大连理工大学 2022-09-27 CN disclosed
WO-1998005961-A1 COMPOUNDS HAVING A PLURALITY OF NITROGENOUS SUBSTITUENTS ISIS PHARMACEUTICALS, INC. (US) 1998-02-12 WO disclosed
WO-1995001346-A1 CHELATING COMPOUNDS AKZO NOBEL N.V. (NL) 1995-01-12 WO disclosed
EP-0527131-A1 CHELANTS NYCOMED SALUTAR, INC. (US) 1993-02-17 EP disclosed
WO-1991010645-A2 CHELANTS COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) 1991-07-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070231318-A1 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES BBOX1, HAVCR2, CYP2E1 CCR1 1040/4885PGK1 2967/4885PGK2 3387/4885
US-12241902-B2 Probes for detection of copper SOD1, SOD3, CELF2 CCR1 3677/4885PGK1 4296/4885PGK2 4088/4885
US-20040162318-A1 Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases BBOX1, HAVCR2, CYP2E1 CCR1 1040/4885PGK1 2967/4885PGK2 3387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.