Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31098473 | 1.00 | CCR1 (0.44) | CCR1HRH4GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL21814461 | 0.98 | GRIN2D (0.45) | CCR1HRH4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL522024 | 0.87 | HRH4 (0.46) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL486201 | 0.87 | CCR1 (0.55) | CCR1HRH4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28610171 | 0.85 | HRH4 (0.44) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL10753045 | 0.85 | GRIN2D (0.48) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24618443 | 0.82 | HRH1 (0.47) | CCR1HRH4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29792037 | 0.82 | HRH1 (0.47) | CCR1HRH4GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL30951158 | 0.80 | HRH1 (0.45) | CCR1HRH4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL25236931 | 0.79 | KCNH2 (0.47) | HRH4GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006033-A1 | ADENOSINE RECEPTOR ANTAGONIST | Xiamen Biotime Biotechnology Co., Ltd. (CN) | 2022-06-01 | — | — | EP | disclosed |
| EP-3253390-B1 | AMINOQUINAZOLINE COMPOUNDS AS A2A ANTAGONIST | MERCK SHARP & DOHME (US) | 2022-04-13 | — | — | EP | disclosed |
| CN-113563245-A | Substituted pyrrolidine compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2021-10-29 | — | — | CN | disclosed |
| WO-2020068583-A1 | PROCESSES FOR MAKING TRIAZOLO [4,5D] PYRAMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | CORVUS PHARMACEUTICALS, INC. (US) | 2020-04-02 | — | — | WO | disclosed |
| WO-2020068583-A1 | PROCESSES FOR MAKING TRIAZOLO [4,5D] PYRAMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | CORVUS PHARMACEUTICALS, INC. (US) | 2020-04-02 | — | — | WO | disclosed |
| US-10441946-B2 | Linear alpha-olefin catalysts and preparation and use thereof | APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) | 2019-10-15 | — | — | US | disclosed |
| US-10138212-B2 | Aminoquinazoline compounds as A2A antagonist | MERCK SHARP & DOHME CORP. (US) | 2018-11-27 | — | — | US | disclosed |
| EP-1551511-B1 | HETEROCYCLIC AROMATIC COMPOUNDS USEFUL AS GROWTH HORMONE SECRETAGOGUES | BRISTOL MYERS SQUIBB CO (US) | 2018-10-24 | — | — | EP | disclosed |
| US-20180147571-A1 | NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF | APALENE TECHNOLOGY CO., LTD. (JIAXING) (CN) | 2018-05-31 | — | — | US | disclosed |
| US-20180147571-A1 | NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF | APALENE TECHNOLOGY CO., LTD. (JIAXING) (CN) | 2018-05-31 | — | — | US | disclosed |
| EP-1720553-A1 | PYRIMIDINE COMPOUNDS AS PURINE RECEPTOR ANTAGONIST | VERNALIS (R&D) LTD (GB) | 2006-11-15 | — | — | EP | disclosed |
| EP-1551511-A4 | HETEROCYCLIC AROMATIC COMPOUNDS USEFUL AS GROWTH HORMONE SECRETAGOGUES | BRISTOL MYERS SQUIBB CO (US) | 2006-08-23 | — | — | EP | disclosed |
| US-20060079549-A1 | Heterocyclic aromatic compounds useful as growth hormone secretagogues | YU GUIXUE | 2006-04-13 | — | — | US | disclosed |
| US-20060063798-A1 | Heterocyclic aromatic compounds useful as growth hormone secretagogues | YU GUIXUE | 2006-03-23 | — | — | US | disclosed |
| WO-2005079801-A1 | PYRIMIDINE COMPOUNDS AS PURINE RECEPTOR ANTAGONIST | VERNALIS (R & D) LTD (GB) | 2005-09-01 | — | — | WO | disclosed |
| EP-1551511-A2 | HETEROCYCLIC AROMATIC COMPOUNDS USEFUL AS GROWTH HORMONE SECRETAGOGUES | Bristol-Myers Squibb Company (US) | 2005-07-13 | — | — | EP | disclosed |
| US-20040147568-A1 | Heterocyclic aromatic compounds useful as growth hormone secretagogues | BRISTOL-MYERS SQUIBB COMPANY | 2004-07-29 | — | — | US | disclosed |
| WO-2004021984-A2 | HETEROCYCLIC AROMATIC COMPOUNDS USEFUL AS GROWTH HORMONE SECRETAGOGUES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-03-18 | — | — | WO | disclosed |
| EP-0527131-A1 | CHELANTS | NYCOMED SALUTAR, INC. (US) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991010645-A2 | CHELANTS | COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) | 1991-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147571-A1 | NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF | UBE2L3, RNF168, AGL | CCR1 1444/4885HRH4 2233/4885GRIN2D 2365/4885 |
| US-20060079549-A1 | Heterocyclic aromatic compounds useful as growth hormone secretagogues | GHSR, GHRHR, NPY1R | CCR1 1623/4885HRH4 211/4885GRIN2D 3810/4885 |
| US-20060063798-A1 | Heterocyclic aromatic compounds useful as growth hormone secretagogues | GHSR, GHRHR, NPY1R | CCR1 1623/4885HRH4 211/4885GRIN2D 3810/4885 |
| US-20040147568-A1 | Heterocyclic aromatic compounds useful as growth hormone secretagogues | GHSR, GHRHR, MUSK | CCR1 1196/4885HRH4 257/4885GRIN2D 3413/4885 |
| US-10441946-B2 | Linear alpha-olefin catalysts and preparation and use thereof | UBE2L3, COG8, ACSL3 | CCR1 1604/4885HRH4 2508/4885GRIN2D 2659/4885 |
| US-10138212-B2 | Aminoquinazoline compounds as A2A antagonist | ADORA2A, ADORA2B, ADORA3 | CCR1 2146/4885HRH4 174/4885GRIN2D 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.