Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1502339 | 0.73 | IDO1 (0.51) | CYP11B1CYP11B2GSK3BDYRK1AIDO1 | |
| Ammonia Solution, Strong SCHEMBL28862527 | 0.72 | IDO1 (0.50) | CYP11B1CYP11B2GSK3BDYRK1AIDO1 | |
| SCHEMBL2945430 | 0.70 | TSHR (0.39) | CYP11B1CYP11B2GSK3BDYRK1AIDO1 | |
| SCHEMBL27843880 | 0.70 | TSHR (0.32) | CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL11060633 | 0.68 | CYP11B1 (0.45) | CYP11B1CYP11B2IDO1ALDH1A1RAB9A | |
| SCHEMBL27501966 | 0.68 | CYP11B1 (0.39) | CYP11B1CYP11B2GSK3BDYRK1AIDO1 | |
| SCHEMBL8054180 | 0.67 | ALDH1A1 (0.41) | CYP11B1CYP11B2GSK3BDYRK1AIDO1 | |
| SCHEMBL28101726 | 0.66 | MAPK14 (0.48) | CYP11B1CYP11B2GSK3BDYRK1AHSP90AA1 | |
| SCHEMBL18837707 | 0.66 | NPC1 (0.40) | CYP11B1CYP11B2IDO1RAB9AGAA | |
| SCHEMBL27984310 | 0.65 | CYP11B1 (0.51) | CYP11B1CYP11B2IDO1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109627219-A | A kind of production method of 5- amino-6-methyl benzimidazolone | 高邮市华宝颜料有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-106398172-A | Wear-resistant PEAK (polyaryletherketone) material and preparation method thereof | 中国科学院长春应用化学研究所 | 2017-02-15 | — | — | CN | disclosed |
| CN-106398171-A | High-strength polyaryletherketone material with stable size and preparation method thereof | 中国科学院长春应用化学研究所 | 2017-02-15 | — | — | CN | disclosed |
| CN-106243676-A | A kind of self-lubricating PAEK material and preparation method thereof | 中国科学院长春应用化学研究所 | 2016-12-21 | — | — | CN | disclosed |
| CN-106243675-A | A kind of antibacterial PAEK material and preparation method thereof | 中国科学院长春应用化学研究所 | 2016-12-21 | — | — | CN | disclosed |