Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | LDLR | P01130 | 1/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27564135 | 0.72 | ALDH1A1 (0.38) | CYP11B1CYP11B2BCHEACHEALDH1A1 | |
| SCHEMBL7512027 | 0.71 | TSHR (0.54) | CYP11B1CYP11B2IDO1LDLRPCSK9 | |
| SCHEMBL7167349 | 0.70 | CYP11B1 (0.48) | CYP11B1CYP11B2IDO1NPC1RAB9A | |
| SCHEMBL28111042 | 0.68 | CYP11B1 (0.41) | CYP11B1CYP11B2IDO1RAB9AALDH1A1 | |
| SCHEMBL4011241 | 0.67 | CYP11B1 (0.52) | CYP11B1CYP11B2IDO1LDLRPCSK9 | |
| SCHEMBL972964 | 0.67 | HPGDS (0.73) | CYP11B1CYP11B2IDO1LDLRPCSK9 | |
| SCHEMBL5324373 | 0.67 | CYP11B1 (0.60) | CYP11B1CYP11B2IDO1HPGDSRAB9A | |
| SCHEMBL12545573 | 0.67 | CYP11B1 (0.55) | CYP11B1CYP11B2IDO1LDLRPCSK9 | |
| SCHEMBL2181000 | 0.66 | FAAH (0.64) | NPC1RAB9ABCHEACHELIPE | |
| SCHEMBL1950645 | 0.65 | CYP11B1 (0.53) | CYP11B1CYP11B2IDO1HPGDSRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483898-A | PERFLUOROBENZOIC ACID OR 1H, 1H-PENTADECAFLOOROOCTYL AMINE AS SPREADING INHIBITORS | AT&T BELL LABORATORIES (US) | 1984-11-20 | — | — | US | disclosed |
| EP-0103617-A4 | LIQUIDS WITH REDUCED SPREADING TENDENCY. | WESTERN ELECTRIC CO (US) | 1984-09-13 | — | — | EP | disclosed |
| EP-0103617-A1 | LIQUIDS WITH REDUCED SPREADING TENDENCY. | WESTERN ELECTRIC CO (US) | 1984-03-28 | — | — | EP | disclosed |
| WO-1983003210-A1 | LIQUIDS WITH REDUCED SPREADING TENDENCY | WESTERN ELECTRIC CO (US) | 1983-09-29 | — | — | WO | disclosed |