SCHEMBL2945430

SCHEMBL2945430

Cc1ccc(-c2cncn2S(=O)(=O)N(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
MEN1 O00255 2/20 0.39
HTT P42858 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
PTGS2 P35354 4/20 0.37
PTGS1 P23219 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.35
HPGD P15428 1/20 0.34
GSK3B P49841 1/20 0.34
DYRK1A Q13627 1/20 0.34
IDO1 P14902 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CYP2C9 P11712 1/20 0.33
PDE4B Q07343 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7512027 0.86 TSHR (0.54) TSHRHTTCYP11B1CYP11B2GAA
SCHEMBL27377525 0.82 TSHR (0.36) TSHRCYP11B1CYP11B2GAAKDM4E
SCHEMBL8054180 0.75 ALDH1A1 (0.41) KMT2ACYP11B1CYP11B2GAAKDM4E
SCHEMBL27408488 0.72 TSHR (0.56) TSHRMEN1HTTKMT2AGAA
SCHEMBL22075692 0.71 PTGS2 (0.36) TSHRHTTCYP11B1CYP11B2GAA
SCHEMBL28111042 0.70 CYP11B1 (0.41) MEN1KMT2ACYP11B1CYP11B2GAA
SCHEMBL1502339 0.69 IDO1 (0.51) CYP11B1CYP11B2GSK3BDYRK1AIDO1
Ammonia Solution, Strong SCHEMBL28862527 0.67 IDO1 (0.50) CYP11B1CYP11B2GSK3BDYRK1AIDO1
SCHEMBL9125147 0.67 ALDH1A1 (0.41) TSHRMEN1HTTKMT2AGAA
SCHEMBL14333780 0.66 DYRK1A (0.40) CYP11B2GAAKDM4EDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425681-A Green synthesis method of cyazofamid 青岛农业大学 2023-07-14 CN claimed
CN-104292166-B The chloro-2-cyano group of 4--N, N-dimethyl-5-p-methylphenyl imidazoles-1-sulphonamide synthetic method XI'AN INST. OF MODERN CHEMISTRY (CN) 2016-04-27 CN claimed
CN-104292166-A Method for synthesizing 4-chloro-2-cyano-N,N-dimethyl-5-p-methylphenylimidazole-1-sulfamide XIAN MODERN CHEMISTRY RES INST 2015-01-21 CN claimed
EP-3848364-B1 MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION SYNGENTA CROP PROTECTION AG (CH) 2024-10-23 EP disclosed
CN-114340374-B Sowing device and method for treating seeds during planting 先正达参股股份有限公司 2024-06-11 CN disclosed
CN-115385860-B Method for synthesizing 2-cyano-5-aryl-1H-imidazole compound 西安近代化学研究所 2024-05-10 CN disclosed
CN-115047107-B Method for detecting residues of fluopicolide, cyazofamid and metabolites thereof on ginseng 山东省农业科学院 2024-03-19 CN disclosed
US-11882834-B2 Microbiocidal thiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 US disclosed
CN-114467928-B Suspending agent containing dimethomorph and cyazofamid and preparation method thereof 青岛润农化工有限公司 2023-12-08 CN disclosed
CN-111406055-B Microbiocidal thiazole derivatives 先正达参股股份有限公司 2023-09-22 CN disclosed
WO-2023139388-A1 METHOD OF IMPROVING PLANT GROWTH UPL Corporation Limited (MU) 2023-07-27 WO disclosed
CN-1427823-A Pyrrolecarboxamides and pyrrolethioamides as fungicides SYNGENTA PARTICIPATIONS AG (CH) 2003-07-02 CN disclosed
CN-1423631-A Phenacylamine derivatives, production thereof and pest controllers containing the derivatives ISHIHARA SANGYO KAISHA (JP) 2003-06-11 CN disclosed
CN-1349381-A Sulfonamide derivatives TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-05-15 CN disclosed
CN-1332608-A Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-23 CN disclosed
CN-1328561-A Pyrimidin-4-enamine as fungicide SINGENTA PARTICIPATION AG (CH) 2001-12-26 CN disclosed
CN-1320124-A Benzazoles: benzoxazole, benzthiazole and benzimidazole derivatives ZENECA LTD (GB) 2001-10-31 CN disclosed
CN-1311774-A Trifluoromethyl pyrrole carboxamides SINGENTA INVOLVEMENT CO LTD (CH) 2001-09-05 CN disclosed
JP-2001181114-A AGRICULTURAL AND HORTICULTURAL BACTERICIDE COMPOSITION KUMIAI CHEM IND CO LTD 2001-07-03 JP disclosed
CN-1226242-A Dihydrofuran carboxamides BAYER AG (DE) 1999-08-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11882834-B2 Microbiocidal thiazole derivatives MSR1, TLR1, IFNG TSHR 1205/4885MEN1 2895/4885HTT 3944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.