Phosphocholine

Phosphocholine

SCHEMBL28111186

C=C(C)C(=O)OCCCC.C[N+](C)(C)CCOP(=O)(O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
LPAR3 Q9UBY5 3/20 0.42
LPAR1 Q92633 2/20 0.42
LPAR2 Q9HBW0 2/20 0.42
LMNA P02545 1/20 0.42
ESR1 P03372 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
CDC25A P30304 1/20 0.42
AGTR1 P30556 1/20 0.42
AKT1 P31749 1/20 0.42
ADRA1A P35348 1/20 0.42
KCNH2 Q12809 1/20 0.42
RAD52 P43351 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
THRB P10828 1/20 0.41
ACHE P22303 3/20 0.40
FABP3 P05413 1/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28906170 0.90 THRB (0.47) TSHRLPAR3LPAR1LPAR2LMNA
Choline SCHEMBL28250828 0.90 TSHR (0.49) TSHRLPAR3LPAR1LPAR2LMNA
SCHEMBL28329138 0.89 TSHR (0.51) TSHRLMNAESR1ADORA3CDC25A
Phosphocholine SCHEMBL1949342 0.89 TSHR (0.51) TSHRLMNAESR1ADORA3CDC25A
SCHEMBL27910406 0.88 TSHR (0.50) TSHRLMNAESR1ADORA3CDC25A
Water SCHEMBL28109847 0.87 TSHR (0.49) TSHRLMNAESR1ADORA3CDC25A
Hydrochloric Acid SCHEMBL6114873 0.87 TSHR (0.66) TSHRLMNAADRA1ARAD52NPSR1
Phosphocholine SCHEMBL15862263 0.86 CHRM5 (0.42) TSHRLMNAADRA1ATHRBACHE
Phosphocholine SCHEMBL28232275 0.86 CHRM5 (0.42) TSHRLMNAADRA1ATHRBACHE
SCHEMBL368310 0.85 LMNA (0.56) TSHRLMNAESR1ADORA3CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114630891-A Methods and compositions for assembly of biological nanopores 斯特拉托斯基因公司 2022-06-14 CN disclosed
CN-114259421-A Daily chemical raw material based on phosphorylcholine polymer and preparation method thereof 江苏奥洁生物科技有限公司 2022-04-01 CN disclosed
CN-106110422-B AIDS immunization therapy absorber 翁炳焕 2019-02-01 CN disclosed
CN-106344986-B Female tire blood group incompatibility treats absorber 翁炳焕 2018-12-04 CN disclosed
CN-106344986-A Maternal-fetal blood group incompatibility treatment adsorber 翁炳焕 2017-01-25 CN disclosed
CN-106110422-A Acquired immune deficiency syndrome (AIDS) immunization therapy adsorber 翁炳焕 2016-11-16 CN disclosed