Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14737356 | 0.78 | ABCB11 (0.33) | LMNAPOLBTDP1KDM4EALDH1A1 | |
| SCHEMBL1372546 | 0.77 | DGAT1 (0.41) | LMNAPOLBTDP1KDM4EALDH1A1 | |
| SCHEMBL14737300 | 0.76 | LMNA (0.38) | LMNAPOLBTDP1KDM4EALDH1A1 | |
| SCHEMBL14737585 | 0.71 | MAPK1 (0.51) | CYP2C9MAPK1 | |
| SCHEMBL31153593 | 0.67 | NR4A2 (0.50) | LMNAKDM4EALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL30570809 | 0.66 | NPSR1 (0.56) | KDM4EALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL14751302 | 0.66 | SYK (0.39) | LMNA | |
| SCHEMBL18534427 | 0.65 | JAK3 (0.34) | POLBALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL29411823 | 0.65 | NPSR1 (0.48) | KDM4EALDH1A1L3MBTL1TSHRMAPK1 | |
| SCHEMBL30050535 | 0.65 | ATR (0.54) | KDM4EALDH1A1L3MBTL1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061973-A | Pyrrolo [2,3-D ] pyrimidinyl, pyrrolo [2,3-B ] pyrazinyl and pyrrolo [2,3-D ] pyridylacrylamide | 辉瑞公司 | 2016-10-26 | — | — | CN | disclosed |