Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CRHBP | P24387 | 1/20 | 0.63 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.59 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 5/20 | 0.57 |
| ▸ | F10 | P00742 | 2/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28099443 | 0.93 | KDM4E (0.65) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL15649531 | 0.85 | KDM4E (0.46) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL1392918 | 0.85 | NOD2 (0.64) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL30585515 | 0.85 | NOD2 (0.64) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL15622712 | 0.85 | KDM4E (0.68) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL8244872 | 0.84 | KDM4E (0.67) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL29463267 | 0.83 | KDM4E (0.65) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL6752352 | 0.82 | KDM4E (0.71) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL28112083 | 0.82 | CNR2 (0.68) | CNR2MCL1ALDH1A1TSHR | |
| SCHEMBL8653460 | 0.82 | KDM4E (0.64) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540817-B | 1,3 dihydro 2H benzimidazole 2 ketone derivatives as the use heterocyclic substituted of respiratory syncytial virus antiviral agent | 爱尔兰詹森科学公司 | 2017-03-01 | — | — | CN | disclosed |