SCHEMBL28112083

SCHEMBL28112083

N#CCCCn1c(C(=O)O)cc2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 7/20 0.68
ALDH1A1 P00352 2/20 0.58
CYP1A2 P05177 1/20 0.58
POLB P06746 1/20 0.58
MCL1 Q07820 4/20 0.57
CCR2 P41597 4/20 0.57
DAO P14920 1/20 0.49
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8709627 0.92 ALDH1A1 (0.60) CNR2ALDH1A1CYP1A2POLBMCL1
SCHEMBL13701158 0.87 CCR2 (0.69) CNR2ALDH1A1CYP1A2POLBMCL1
SCHEMBL15649683 0.83 CCR2 (0.58) CNR2MCL1CCR2
SCHEMBL2400013 0.82 CCR2 (0.63) CNR2ALDH1A1CYP1A2POLBMCL1
SCHEMBL6752492 0.82 ALDH1A1 (0.63) CNR2ALDH1A1CYP1A2POLBMCL1
SCHEMBL28111591 0.82 KDM4E (0.63) CNR2ALDH1A1MCL1TSHR
SCHEMBL28257487 0.81 CNR2 (1.00) CNR2ALDH1A1TSHR
SCHEMBL10757133 0.81 ALDH1A1 (0.66) CNR2ALDH1A1CYP1A2POLBMCL1
SCHEMBL6755386 0.81 CCR2 (0.66) CNR2ALDH1A1CYP1A2POLBMCL1
SCHEMBL28004668 0.81 CNR2 (0.47) CNR2ALDH1A1CYP1A2POLBCCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104540817-B 1,3 dihydro 2H benzimidazole 2 ketone derivatives as the use heterocyclic substituted of respiratory syncytial virus antiviral agent 爱尔兰詹森科学公司 2017-03-01 CN disclosed